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Abstract


INTERNATIONAL DENTAL JOURNAL OF STUDENTS RESEARCH - VOLUME 2 ISSUE 2, Dec-June 2014

Pages: 05-09

BIOACTIVE GLASSES FOR BONE TISSUE ENGINEERING APPLICATION

 

Author: Furqan Ali Shah1, 2, 3

Category: Original Research

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Abstract:

Bioactive glasses are useful materials as synthetic bone graft substitutes due to their potential for osseoinduction and osseoconduction. The ability of these materials to chemically bond to bone is characterized by surface apatite formation. In this paper, the bioactivity of two bioactive glasses has been evaluated in serum supplemented cell culture medium simulating near-physiological conditions and analysed by pH measurements, ICP-ES, FT-IR and XRD. The results show how Bioglass 45S5 that is considered maximally bioactive by many other studies, failed to form apatite in such conditions, while a slightly different glass composition was able to form detectable crystalline apatite in the same conditions, indicating the effect of minor changes in chemical composition on the bioactivity of such materials.

 

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